|
|
C20916 <=> Tabtoxin
|
not assigned
|
–
|
| |
KEGG:
R10890
|
|
|
|
(S)-2-Hydroxy-2-(4-hydroxyphenyl)acetate + O2 <=> 4-hydroxyphenylglyoxylate + H2O2
|
1.1.3.46
4-hydroxymandelate oxidase
|
–
|
| |
BRENDA:
BR50849
KEGG:
R06633
MetaCyc:
RXN-15300
|
|
|
|
isonocardicin_C <=> nocardicin_C
|
5.1.1.14
nocardicin A epimerase
|
–
|
| |
BRENDA:
BR51656
KEGG:
R10883
MetaCyc:
RXN-17843
|
|
|
|
C20914 + L-threonine <=> C20915
|
not assigned
|
–
|
| |
KEGG:
R10888
|
|
|
|
C20911 <=> C20912
|
not assigned
|
–
|
| |
KEGG:
R10885
|
|
|
|
nocardicin_C + 2 NADPH + 2 H+ + 2 O2 <=> nocardicin_A + 2 NADP+ + 3 H2O
|
1.14.13
|
–
|
| |
KEGG:
R10882
|
|
|
|
4-hydroxyphenylpyruvate + O2 <=> (S)-2-Hydroxy-2-(4-hydroxyphenyl)acetate + CO2
|
1.13.11.46
4-hydroxymandelate synthase
|
–
|
| |
BRENDA:
BR29129
KEGG:
R06632
|
|
|
|
5 ATP + 3 L-4-hydroxyphenylglycine + L-arginine + L-serine + H2O <=> 5 AMP + 5 diphosphate + nocardicin_G + L-4-Hydroxyphenylglycyl-L-arginine
|
not assigned
|
–
|
| |
KEGG:
R10880
|
|
|
|
C20912 <=> C20913
|
not assigned
|
–
|
| |
KEGG:
R10886
|
|
|
|
Tabtoxinine-beta-lactam <=> Tabtoxinine-delta-lactam
|
not assigned
|
–
|
| |
KEGG:
R10894
MetaCyc:
RXN-19258
|
|
|
|
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NADP+ + H2O <=> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+
|
1.17.1.8
4-hydroxy-tetrahydrodipicolinate reductase
|
–
|
| |
BRENDA:
BR36807
KEGG:
R04199
MetaCyc:
RXN-14014
|
|
|
|
Tabtoxin + H2O <=> Tabtoxinine-beta-lactam + L-threonine
|
3.4
3.4.11
|
–
–
|
| |
KEGG:
R10891
MetaCyc:
RXN-19255
|
|
|
|
ATP + Tabtoxinine-beta-lactam + L-threonine <=> ADP + phosphate + Tabtoxin
|
6.3.2
|
–
|
| |
KEGG:
R10892
|
|
|
|
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD+ + H2O <=> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADH + H+
|
1.17.1.8
4-hydroxy-tetrahydrodipicolinate reductase
|
–
|
| |
BRENDA:
BR36807-a
KEGG:
R04198
MetaCyc:
RXN-14014_WOP
|
|
|
|
Tabtoxin <=> Isotabtoxin
|
not assigned
|
–
|
| |
KEGG:
R10895
MetaCyc:
RXN-19259
|
|
|
|
acetyl-CoA + Tabtoxinine-beta-lactam <=> N1-Acetyl-tabtoxinine-beta-lactam + CoA + H+
|
2.3.1
|
–
|
| |
KEGG:
R10893
MetaCyc:
RXN-19257
|
|
|
|
L-N-acetyl-2-amino-6-oxopimelate <=> C20911
|
not assigned
|
–
|
| |
KEGG:
R10884
|
|
|
|
nocardicin_G <=> nocardicin_E
|
not assigned
|
–
|
| |
KEGG:
R10903
|
|
|
|
S-adenosyl-L-methionine + nocardicin_E <=> H+ + isonocardicin_A + S-methyl-5''-thioadenosine
|
2.5.1.38
isonocardicin synthase
|
–
|
| |
BRENDA:
BS323276
KEGG:
R03072
MetaCyc:
ISONOCARDICIN-SYNTHASE-RXN;
RXN-17844
|
|
|
|
L-aspartate + ATP <=> L-4-aspartyl_phosphate + ADP
|
2.7.2.4
aspartate kinase
|
–
|
| |
BRENDA:
BR47827
KEGG:
R00480
MetaCyc:
ASPARTATEKIN-RXN
SABIO-RK:
912
|
|
|
|
acetyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O <=> CoA + L-N-acetyl-2-amino-6-oxopimelate
|
2.3.1
2.3.1.89
tetrahydrodipicolinate N-acetyltransferase
|
–
–
|
| |
BRENDA:
BR44091
KEGG:
R04364
MetaCyc:
2.3.1.89-RXN
|
|
|
|
C20913 <=> C20914 + CO2
|
4.1.1
|
–
|
| |
KEGG:
R10887
|
|
|
|
C20915 <=> C20916
|
not assigned
|
–
|
| |
KEGG:
R10889
|
|
|
|
H+ + sulfate + ATP <=> adenosine_5''-phosphosulfate + diphosphate
|
2.7.7.4
sulfate adenylyltransferase
|
–
|
| |
BRENDA:
BR47884
KEGG:
R00529
MetaCyc:
SULFATE-ADENYLYLTRANS-RXN
SABIO-RK:
947
|
|
|
|
pyruvate + L-aspartate_4-semialdehyde <=> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O + H+
|
4.3.3.7
4-hydroxy-tetrahydrodipicolinate synthase
|
–
|
| |
BRENDA:
BR3399
KEGG:
R10147
MetaCyc:
DIHYDRODIPICSYN-RXN
|
|
|
|
S-adenosyl-L-methionine + nocardicin_G <=> isonocardicin_C + S-methyl-5''-thioadenosine + H+
|
2.5.1.38
isonocardicin synthase
|
–
|
| |
BRENDA:
BR44284
KEGG:
R10881
MetaCyc:
RXN-17837
|
|
|
|
isonocardicin_A <=> nocardicin_A
|
5.1.1.14
nocardicin A epimerase
|
–
|
| |
BRENDA:
BR167
KEGG:
R03073
MetaCyc:
NOCARDICIN-A-EPIMERASE-RXN
|
|
|
|
4-hydroxyphenylglyoxylate + L-tyrosine <=> L-4-hydroxyphenylglycine + 4-hydroxyphenylpyruvate
|
2.6.1.103
(S)-3,5-dihydroxyphenylglycine transaminase
2.6.1.B17
|
–
–
|
| |
BRENDA:
BR52009
KEGG:
R06626
|
|
